comment-regionisn't actually part of CC Mode - it is given a CC Mode binding for convenience.
comment-column(see Options for Comments) and the variables below. Finally, position the point after the comment starter. C-u M-; kills any comment on the current line, together with any whitespace before it. This is a standard Emacs command, but CC Mode enhances it a bit with two variables:
This style variable allows you to vary the column that M-; puts the comment at, depending on what sort of code is on the line, and possibly the indentation of any similar comment on the preceding line. It is an association list that maps different types of lines to actions describing how they should be handled. If a certain line type isn't present on the list then the line is indented to the column specified by
See the documentation string for a full description of this variable (use C-h v c-indent-comment-alist).
Normally, when this style variable is
nil, M-; will indent comment-only lines according to
c-indent-comment-alist, just as it does with lines where other code precede the comments. However, if you want it to act just like <TAB> for comment-only lines you can get that by setting
c-indent-comment-alistwon't be consulted at all for comment-only lines.
 The name of this command varies between (X)Emacs versions.